Testing and Diagnostics Library

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Showing 25–48 of 164

Nature - npj AgingApr 4, 2026

scAgeClock: a single-cell transcriptome-based human aging clock model using gated multi-head attention neural networks

Researchers developed scAgeClock, a machine learning model that measures aging at the single-cell level by analyzing gene expression patterns. This cellular-resolution aging clock offers a novel method to detect age-related changes before systemic symptoms emerge, with potential applications in monitoring intervention efficacy and identifying individuals at accelerated aging risk.

Longevity.TechnologyMar 25, 2026

Alnylam advances ATTR-CM detection with Viz.ai and AHA support

Alnylam is implementing AI-enabled diagnostic pathways and clinical learning collaboratives to accelerate detection of transthyretin-mediated amyloid cardiomyopathy (ATTR-CM), a progressive cardiac condition often diagnosed late. Earlier detection of this condition directly impacts treatment outcomes and disease trajectory, making systematic screening improvements clinically significant.

Longevity.TechnologyApr 14, 2026

AI sharpens Alzheimer’s PET readouts

An artificial intelligence framework called interpretable adversarial decomposition learning (ADL) improves the clinical utility of Alzheimer's PET scans by filtering noise from disease signal, producing an ADAD score that correlates more closely with cognitive decline and neurodegeneration than traditional scoring methods. This advancement addresses a persistent gap between imaging findings and actual patient outcomes.

Longevity.TechnologyFeb 25, 2026

Syndex Bio’s mcPCR opens new path for early disease detection

Syndex Bio's mcPCR technology preserves DNA methylation patterns during amplification, enabling detection of disease-associated epigenetic changes from minimal samples. This advance addresses a critical gap in early disease detection and biological age assessment, with implications spanning oncology, prenatal diagnostics, and longevity research.

LT WireMay 8, 2026

Executive Health program condenses three months of testing into six hours

Biograph's Executive Physical consolidates comprehensive cardiovascular, metabolic, cancer, and neurological screening into a single six-hour appointment using whole-body MRI, advanced CT, and biomarker analysis. This integrated approach identifies significant health findings in approximately 17 percent of participants and demonstrates measurable metabolic improvements in follow-up assessments.

Longevity.TechnologyFeb 12, 2026

AI, genomics and CRISPR signal a new phase of biological innovation

AI-driven pattern recognition combined with expanded genomic sequencing and CRISPR gene editing is accelerating drug discovery and precision medicine by generating large datasets for machine learning models. This convergence enables shorter development cycles and more targeted therapeutic interventions based on individual genetic profiles.

Longevity.TechnologyFeb 13, 2026

Human brain aging decoded through living tissue

Researchers mapped how living human brain cells coordinate structural changes across the lifespan, revealing that brain aging is an active, regulated biological process rather than passive deterioration. This represents the first large-scale analysis of living tissue, enabling identification of molecular targets for intervention in age-related neurological decline.

Longevity.TechnologyMar 12, 2026

AI app puts longevity data in your pocket

Human Longevity has launched a mobile application that consolidates clinical data, biomarkers, genetic information, and imaging results into a continuous health record accessible to users. The platform uses AI to identify patterns across longitudinal data, shifting preventive health assessment from episodic annual checkups to real-time risk monitoring and interpretation.

Longevity.TechnologyApr 23, 2026

Curve Biosciences advances AI blood diagnostics

Curve Biosciences has developed AI-powered blood diagnostics that detect organ-specific disease signals by analyzing epigenetic markers in circulating DNA, validated in a 1,482-patient cirrhosis study. This approach shifts chronic disease monitoring from episodic snapshots to continuous molecular tracking of organ stress and aging progression.

Longevity.TechnologyFeb 23, 2026

AI’s role in the next era of longevity biotech

Artificial intelligence is compressing drug discovery timelines from four to five years to approximately fourteen months by automating target identification, molecular design, and clinical trial prediction. This acceleration has direct implications for longevity therapeutics, where speed to market can determine whether interventions reach patients before age-related decline progresses beyond intervention points.

LT WireMar 19, 2026

ADDF launches new phase of $150m Alzheimer’s diagnostics accelerator

The Alzheimer's Drug Discovery Foundation has committed an additional $50 million to its Diagnostics Accelerator program, now totaling $150 million, to advance blood-based biomarkers, multi-marker panels, and AI-driven diagnostic tools for Alzheimer's disease. This investment targets earlier detection and disease monitoring to enable preventive interventions and combination therapies before irreversible neurodegeneration occurs.

LT WireMay 29, 2026

AI Foundation Models Decode Multi-System Health Data

Human Longevity Inc. established Human Life Foundation Models to develop multimodal AI models for disease prediction and aging biology using de-identified clinical and multi-omic datasets. This infrastructure addresses a critical gap in personalized risk assessment and intervention discovery at scale.

Peter Attia MDMar 7, 2026

A failed endpoint is not a failed technology

GRAIL's cancer screening trial missed its primary composite endpoint, but subgroup analysis reveals meaningful detection rates in specific cancer types, indicating the technology may have clinical value despite the headline failure. Understanding what the data actually shows versus what was reported requires interpreting signal-to-noise in early detection research.

Longevity.TechnologyFeb 18, 2026

Listening to biology’s early whispers

Chronic diseases develop through years of subtle, cumulative molecular drift before clinical diagnosis. The Buck Institute proposes longitudinal, AI-driven monitoring against individual baselines—treating each person as their own biological reference—to detect these early deviations rather than waiting for symptomatic presentation.

LT WireMay 11, 2026

Abu Dhabi’s “Future Health” initiative targets longevity, predictive care

Abu Dhabi is establishing a large-scale health infrastructure combining genomic, phenotypic, and wearable data with AI to enable predictive care and accelerate drug discovery. This represents a shift toward population-level early detection and prevention rather than reactive treatment models.

Longevity.TechnologyFeb 19, 2026

AI-driven food app targets disease prevention and aging

Foodhak uses AI-driven personalization to translate nutrition science into daily food guidance aligned with individual health markers and goals. The approach positions food as preventive medicine rather than caloric constraint, addressing a systemic gap where most food choices optimize for taste and cost rather than long-term health outcomes.

Wiley Aging CellMar 7, 2026

The Immune‐Autonomic Interface in Aging: Baseline Immune Profile Shapes Cardiac Autonomic Response to Exercise

Baseline immune cell profiles in older adults predict how their heart rate variability responds to acute exercise stress. This immune-autonomic relationship reveals why individuals show heterogeneous physiological resilience during aging, informing personalized intervention strategies.

Longevity.TechnologyMar 5, 2026

Cognitive toolkit detects early Alzheimer’s signs

Researchers developed a Mandarin-language cognitive toolkit to detect early Alzheimer's signs in older Chinese Americans, addressing diagnostic gaps created by language and cultural bias in English-based assessments. The validated tests correlate with English measures and early blood-based biomarkers, enabling earlier intervention and broader research participation in underserved communities.

Longevity.TechnologyMar 24, 2026

Perplexity enters the consumer health AI arena

Perplexity has launched an AI-powered health platform that aggregates fragmented health data from medical records, wearables, and provider systems into a unified dashboard, enabling personalized health insights grounded in individual biomarkers and trends. This addresses a critical infrastructure gap in longevity practice: the ability to contextualize health signals across time and across systems, moving beyond isolated data points toward pattern recognition that supports earlier intervention.

Longevity.TechnologyMar 30, 2026

PREMAZ expands early brain screening through Health is One

PREMAZ, a digital cognitive assessment tool, has partnered with Health is One to integrate early brain screening into everyday wellness services rather than clinical settings. The platform measures memory precision—the sharpness and reliability of recall—to detect subtle cognitive changes before decline becomes clinically apparent, shifting brain health assessment from reactive to preventive.

Peter Attia MDApr 28, 2026

Reducing cardiovascular risk: a playbook for lipid-lowering pharmacotherapy

A systematic approach to lipid-lowering pharmacotherapy uses risk stratification and a six-step protocol to guide drug selection and escalation, optimizing cardiovascular protection across heterogeneous patient populations. This framework addresses the gap between guideline recommendations and individualized clinical decision-making in managing atherosclerotic cardiovascular disease risk.

Longevity.TechnologyApr 9, 2026

AliveCor expands AI 12-lead cardiac diagnostics to Vietnam

AliveCor's Kardia 12L, an AI-powered portable 12-lead electrocardiogram system, has secured regulatory registration in Vietnam to enable hospital-grade cardiac diagnostics at point of care. The device reduces acquisition time by approximately 30% and simplifies electrode setup, allowing earlier detection of arrhythmias, myocardial infarction, and cardiac ischemia in community and outpatient settings.

LT WireApr 17, 2026

Life Time rolls out SpiroFit metabolic testing to country clubs

Life Time is deploying SpiroFit, a cordless wearable metabolic testing system, across 190 clubs to measure VO2 max and fuel utilization during exercise. The technology generates personalized heart-rate training zones with lab-grade accuracy, enabling members to optimize training intensity and metabolic efficiency.

Nature AgingMar 3, 2026

Multi-tissue transcriptomic aging atlas reveals predictive aging biomarkers in the killifish

Researchers created a multi-tissue transcriptomic atlas across thirteen tissues in African turquoise killifish at six life stages, identifying molecular patterns of aging that vary by tissue type and sex. This resource establishes predictive biomarkers for aging dynamics and demonstrates how systemic and local factors drive age-related changes across the organism.

Biological EDGE

Biohacking Starts With NO